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Profile
| Academic position | Associate Professor, Senior Lecturer, Reader |
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| Research fields | Cell Biology,Biochemistry |
| Keywords | membrane fusion, phagosome maturation, reconstitution assays, network modelling |
Current contact address
| Country | Argentina |
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| City | Mendoza |
| Institution | Universidad Nacional de Cuyo |
| Institute | Instituto de Histologia y Embriologia (IHEM-CONICET) |
Host during sponsorship
| Dr. Gareth Griffiths | European Molecular Biology Laboratory (EMBL) Heidelberg, Europäisches Laboratorium für Molekularbiologie (EMBL), Heidelberg |
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| Start of initial sponsorship | 01/11/2006 |
Programme(s)
| 2006 | Humboldt Research Award Programme |
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Nominator's project description
| Professor Mayorga has been an important protagonist in the development of the Cell Biology field of Intracellular Trafficking. He has been particularly successful in developing in vitro assays that reconstitute specific membrane fusion events. These model systems have been very useful to understand several aspects of the molecular machinery participating in endocytosis and pahgocytosis. In the last few years, his laboratory has worldwide leaded the characterization of the membrane fusion event occurring during the acrosomal exocytosis in sperm cells. |
Publications (partial selection)
| 2008 | Mark Kühnel, Luis S. Mayorga, Thomas Dandekar, Juilee Thakar, Roland Schwarz, Elsa Anes, Gareth Griffiths, and Jens Reich: Modelling phagosomal lipid networks that regulate actin assembly. In: BMC Systems Biology, 2008, |
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| 2008 | Jordao, L., Bleck 1, C.K.E., Mayorga, L., Griffiths, G., and Anes, E. On the killing of mycobacteria by macrophages. In: Cellular Microbiology, 2008, 529-548 |
| 2007 | Gareth Griffiths and Luis S. Mayorga: Phagosome proteomes open the way to a better understanding of phagosome function. In: Genome Biology, 2007, 207 |